Pharmaceutical Shock Freezer and Thawer TPSU 1000L (-40°C to -85°C)

GENERAL OVER VIEW

Thalheimer has innovated the new technology and production of Medical Deep, Ultra Low Temperature, Freezer and the fastest Shock freezer down to – 85ºC in cooperation with specialist in the field s of electronics and thermodynamics.
All units are complied with UNI EN 61010-1/A2 (CEI 66-5), CEI EN 61326-1, R egulations on safety for laboratory equipment and ISO 9001:2008 certified manufacturer.
Different models and sizes have been pre-designed and considered as standard models offered by Thalheimer.
We have three models within the range of Deep and Ultra Low Temperature Freezers: horizontal, vertical and under counter units. Thalheimer produce different sizes from the above models and those are in the range of 85L for the under counter till 800 L which is considered as the biggest standard model.
For Shock freezer, Thalheimer offers very wide range of models starting from 100 Liter till 1000 Liter for different applications of laboratory and Hospital/Medical use as well as for Research and Development institutes and Pharmaceutical industries.
Thalheimer always offer custom made design with different sizes and model based on our client’s requirement and expectation.
In general the time required to cool down the inner chamber of the ULT freezer from ambient temperatures to the selected set temperature of -80°C to -85°C is mainly depending on the type of insulation, the efficiency of the compressor system as well as the installed metal shelves within the freezer. Thalheimer’s TPSU unit Shock freezers are able to cool down within 2.15 to 3.30 hours and the product freezing in 40-45 minutes.

Optional feature: Blast Freezer / Thawer (downstream processing of biopharmaceutical products )

The system described is a Blast Freezer & Thawer. It is used for downstream processing of bio-pharmaceutical products (proteins). The Blast Freezer / Thawer enables fast, uniform bulk freezing and thawing of Protein or products contained in a variety of containers, (bags, bottles or any size containers) such as single use system (SUS), polycarbonate vessels or polypropylene vessels.

The Blast Freezer & Thawer is used for the defined freezing of bottles with bio-pharmaceutical content. During a freezing process the pharmaceutical product is placed in the freezing chamber. The same occurs when thawing the product. A pre-defined temperature profile will be executed. Finally the bottles will be deep frozen and can be processed further for shipment. After storage, the bottles removed from a -80°C freezer will be thawed. Both freezing and thawing should occur very fast using convective air (“blast”) of -80°C (freezing) or +25 – 30°C (thawing).

Therefore, the blast freezer & thawer must have a thawing function, which allows a controlled warming and defrosting of goods to temperatures up to + 25 – 30°C with high precision (no temperature cycling outside of this range).

STRUCTURE

– External cabinet made of zinc-plated and/or enameled steel sheets, o r, upon request, SI 304 stainless steel satin finish.
– Insulation in non-CFC, non-HCFC foamed polyurethane
– Internal casing in AISI 304 (or AISI 316 upon r equest) stainless steel, with polished exter nal BA finish for maximum resistance and cleanliness; LIFETIME WARRANTY ON STEEL PARTS
– Triple-step seal in silicone rubber for greatest prevention against air loss and ice formation; gaskets with almost unlimited durability.

– Gasket heating by means of the r efrigerant pipes on the overheated-steam side; the safest solution against ice formation, more reliable and with greater energy saving (in fact, it does not use additional sources of heat like electric resistances, etc.)
– Complete reheating compensation valve to equalize inter nal and external pressure after opening and closing the door: greatly facilitates being able to open the door after it has been opened not long ago.
– Four internal stainless steel shelves, standard in vertical models
– Insulated counter doors (in vertical models) with 20-mm. poly urethane foam, to minimize cold loss when the external door is opened;
– Insulation panels (in horizontal models) with 20-mm. polyur ethane foam, to minimize cold loss when the external door is opened;
– Highly ergonomic closing handle (in vertical models) to facilitate closi ng: just one hand and minimum force applied
– Locking handle with self-raising hinges (in horizontal models ) for maximum ease when closing and maximum operator safety.
– Lock and key for all locks
– Loading System: Our innovative solution gives you the possibility to quickly load the freezer with the help of a trolley. This way the whole racket system is inserted into the freezer, giving you the chance to freeze the plasma, in the fastest time, in 2.15 minutes and for the product freezing takes up to 40 minutes.
– Pivoting wheels for maximum freezer maneuverability inside the laboratory
– Insulation with CFC- and HCFC-free polyurethane resin foamed on site, with an average thickness above 140 mm
– Lock with transponder/badge available (optional); the PK (Per sonal Key) device comes complete with badge reader, management electronics, stabilized power supply at 12 Vdc 3 A and microelectronic security pistons. It is integrated with the closing system.
– Optional: Trolley loading system for Shock Freezer